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Erucic acid

CAS No. 112-86-7

Erucic acid ( cis-13-docosenoic acid;13(Z)-Docosenoic Acid;Prifac 2990 )

Catalog No. M19744 CAS No. 112-86-7

Increased levels of erucic acid (22:1n9) have been found in the red blood cell membranes of autistic subjects with developmental regression.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Erucic acid
  • Note
    Research use only not for human use.
  • Brief Description
    Increased levels of erucic acid (22:1n9) have been found in the red blood cell membranes of autistic subjects with developmental regression.
  • Description
    Increased levels of erucic acid (22:1n9) have been found in the red blood cell membranes of autistic subjects with developmental regression (PMID: 16581239 ). Erucic acid is broken down long-chain acyl-coenzyme A (CoA) dehydrogenase which is produced in the liver. This enzyme breaks this long chain fatty acid into shorter-chain fatty acids. human infants have relatively low amounts of this enzyme and because of this babies should not be given foods high in erucic acid. Erucic acid is found to be associated with isovaleric acidemia which is an inborn error of metabolism.
  • Synonyms
    cis-13-docosenoic acid;13(Z)-Docosenoic Acid;Prifac 2990
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Endogenous Metabolite
  • Recptor
    Human Endogenous Metabolite
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    112-86-7
  • Formula Weight
    338.57
  • Molecular Formula
    C22H42O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:197.9 mM
  • SMILES
    CCCCCCCC\C=C/CCCCCCCCCCCC(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Aubourg P Adamsbaum C Lavallardrousseau M C et al. A two-year trial of oleic and erucic acids ("Lorenzo's oil") as treatment for adrenomyeloneuropathy.[J]. New England Journal of Medicine 1993 329(11):745.
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